One of the foremost intellectuals of his generation, French philosopher of science Michel Serres (1930–2019) broke free from disciplinary dogmas, boundaries, and definitions. The participants on this panel seek to illuminate the inspiration and riddles that Serres’s writing has had on their own work. They will examine some of Serres’s key interrogations of human existence, hinging on conceptual meridians like porosity, the parasite, and translation.